Some others:
Blocked caves throughout Foothills.
Chamelopods, who is the "master", will he return?
Drake Den - why are these Fire Drakes slaughters? (no IC incentive to rescue people)
Greymyr Chief, and what the Greymyr think they are protecting.
Items with no known use: Skein of silk. Shiny medallion. Blue bauble. Herpetid hide.
Jade Noids cave, ends abruptly at a rock wall.
New East forest South edge has an apparent 1-way exit from somewhere unknown to the South ("your way is blocked by dense underbrush") - from Marsh? Savanna? new area?
North plains 1 East of the Chamelopod entrance - there is a treed-off sction (NW corner) that is un-enterable but looks like an area.
NPCs giving hints at, nothing? Cairo. Boondoggle. Torgo.
Original Mirror castle, and the places its mirrors led to. Are these just fading dreams or are they real places?
Pathfinding (gotta say it, although I think we are finally making real progress)
Sarra. no trace of Lady Sarra's final resting place.
Un-openned islands.
Wells in all 3 passes un-enterable despite having ladders.
What lies East of Dunes/Savanna/Passes/Northeast Forest/North Plains (other than Orga territory)?
Azriel